Article
Early disease onset is predicted by a higher genetic risk for lupus and is associated with a more severe phenotype in lupus patients.
Annals of the rheumatic diseases - 1 Jan 2011
Webb Ryan, Kelly Jennifer A, Somers Emily C, Hughes Travis, Kaufman Kenneth M, Sanchez Elena, Nath Swapan K, Bruner Gail, Alarcón-Riquelme Marta E, Gilkeson Gary S, Kamen Diane L, Richardson Bruce C, Harley John B, Sawalha Amr H
Abstract excerpt
BACKGROUND: Systemic lupus erythematosus (SLE) is a chronic, multiorgan, autoimmune disease that affects people of all ages and ethnicities. OBJECTIVES: To explore the relationship between age at disease onset and many of the diverse manifestations of SLE. Additionally, to determine the relationship between age of disease onset and genetic risk in patients with SLE. METHODS: The relationship between the age at...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.