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Article

Prognostic impact of somatic mutations in diffuse large B-cell lymphoma and relationship to cell-of-origin: data from the phase III GOYA study.

Haematologica - 1 Sept 2020

Bolen Christopher R, Klanova Magdalena, Trneny Marek, Sehn Laurie H, He Jie, Tong Jing, Paulson Joseph N, Kim Eugene, Vitolo Umberto, Di Rocco Alice, Fingerle-Rowson Günter, Nielsen Tina, Lenz Georg, Oestergaard Mikkel Z

Abstract excerpt

Diffuse large B-cell lymphoma represents a biologically and clinically heterogeneous diagnostic category with well-defined cell-of-origin subtypes. Using data from the GOYA study (NCT01287741), we characterized the mutational profile of diffuse large B-cell lymphoma and evaluated the prognostic impact of somatic mutations in relation to cell-of-origin. Targeted DNA next-generation sequencing was performed in 499...

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Identifiers

PMID: 33054054
DOI: 10.3324/haematol.2019.227892
PMCID: PMC7556630

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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