Article
Short branched-chain C6 carboxylic acids result in increased growth, novel 'unnatural' fatty acids and increased membrane fluidity in a Listeria monocytogenes branched-chain fatty acid-deficient mutant.
Biochimica et biophysica acta - 1 Oct 2015
Sen Suranjana, Sirobhushanam Sirisha, Hantak Michael P, Lawrence Peter, Brenna J Thomas, Gatto Craig, Wilkinson Brian J
Abstract excerpt
Listeria monocytogenes is a psychrotolerant food borne pathogen, responsible for the high fatality disease listeriosis, and expensive food product recalls. Branched-chain fatty acids (BCFAs) of the membrane play a critical role in providing appropriate membrane fluidity and optimum membrane biophysics. The fatty acid composition of a BCFA-deficient mutant is characterized by high amounts of straight-chain fatty...
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