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Article

Gene-set Enrichment with Mathematical Biology (GEMB).

GigaScience - 9 Oct 2020

Cochran Amy L, Nieser Kenneth J, Forger Daniel B, Zöllner Sebastian, McInnis Melvin G

Abstract excerpt

BACKGROUND: Gene-set analyses measure the association between a disease of interest and a "set" of genes related to a biological pathway. These analyses often incorporate gene network properties to account for differential contributions of each gene. We extend this concept further-defining gene contributions based on biophysical properties-by leveraging mathematical models of biology to predict the effects of...

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Identifiers

PMID: 33034635
DOI: 10.1093/gigascience/giaa091
PMCID: PMC7546080

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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