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Article

A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia.

Journal of medical genetics - 1 Feb 2012

Jia Peilin, Wang Lily, Fanous Ayman H, Chen Xiangning, Kendler Kenneth S, Zhao Zhongming

Abstract excerpt

BACKGROUND: After the recent successes of genome-wide association studies (GWAS), one key challenge is to identify genetic variants that might have a significant joint effect on complex diseases but have failed to be identified individually due to weak to moderate marginal effect. One popular and effective approach is gene set based analysis, which investigates the joint effect of multiple functionally related...

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Identifiers

PMID: 22187495
DOI: 10.1136/jmedgenet-2011-100397

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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