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Article

Ion channels and schizophrenia: a gene set-based analytic approach to GWAS data for biological hypothesis testing.

Human genetics - 1 Mar 2012

Askland Kathleen, Read Cynthia, O'Connell Chloe, Moore Jason H

Abstract excerpt

Schizophrenia is a complex genetic disorder. Gene set-based analytic (GSA) methods have been widely applied for exploratory analyses of large, high-throughput datasets, but less commonly employed for biological hypothesis testing. Our primary hypothesis is that variation in ion channel genes contribute to the genetic susceptibility to schizophrenia. We applied Exploratory Visual Analysis (EVA), one GSA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 21866342
DOI: 10.1007/s00439-011-1082-x
PMCID: PMC3278516

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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