Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Notch and disease: a growing field.

Seminars in cell & developmental biology - 1 Jun 2012

Louvi Angeliki, Artavanis-Tsakonas Spyros

Abstract excerpt

Signals through the Notch receptors are used throughout development to control cellular fate choices. Our intention here is to provide an overview of the involvement of Notch signaling in human disease, which, keeping pace with the known biology of the pathway, manifests itself in a pleiotropic fashion. A pathway with such broad action in normal development, a profound involvement in the biology of adult stem...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alagille Syndrome
Share to Bone Diseases, Metabolic
Share to CADASIL

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Cardiovascular Diseases

Share to Genetic Pleiotropy

Share to Neoplasms

Share to Oncogenes

Share to Receptors, Notch

Source

Open in PubMed Open full text

Identifiers

PMID: 22373641
DOI: 10.1016/j.semcdb.2012.02.005
PMCID: PMC4369912

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Notch and disease: a growing field.PMID 22373641Read ↗

Notch signalling pathway and human diseasesSemantic proximity Read ↗

Notch signaling: control of cell communication and cell fate.Semantic proximity Read ↗

Notch signaling in human development and disease.Semantic proximity Read ↗

[Molecular mechanisms and developmental functions of notch signaling].Semantic proximity Read ↗

Notch -- a goldilocks signaling pathway in disease and cancer therapy.Semantic proximity Read ↗

Notch signaling.Semantic proximity Read ↗

Notch signaling in development and disease.Semantic proximity Read ↗

Notch Pathway: A Journey from Notching Phenotypes to Cancer Immunotherapy.Semantic proximity Read ↗

Notch and interacting signalling pathways in cardiac development, disease, and regenerationSemantic proximity Read ↗

The developmental biology of genetic Notch disordersSemantic proximity Read ↗

NOTCH Signaling Pathway: Occurrence, Mechanism, and NOTCH-Directed Therapy for the Management of CancerSemantic proximity Read ↗

Notch signaling and ageing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.