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Article

The potyviral silencing suppressor HCPro recruits and employs host ARGONAUTE1 in pro-viral functions.

PLoS pathogens - 1 Oct 2020

Pollari Maija, De Swarnalok, Wang Aiming, Mäkinen Kristiina

Abstract excerpt

In this study, we demonstrate a novel pro-viral role for the Nicotiana benthamiana ARGONAUTE 1 (AGO1) in potyvirus infection. AGO1 strongly enhanced potato virus A (PVA) particle production and benefited the infection when supplied in excess. We subsequently identified the potyviral silencing suppressor, helper-component protease (HCPro), as the recruiter of host AGO1. After the identification of a conserved...

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Identifiers

PMID: 33031436
DOI: 10.1371/journal.ppat.1008965
PMCID: PMC7575100

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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