Article
Viral Protein Inhibits RISC Activity by Argonaute Binding through Conserved WG/GW Motifs
15 Jul 2010
Abstract excerpt
RNA silencing is an evolutionarily conserved sequence-specific gene-inactivation system that also functions as an antiviral mechanism in higher plants and insects. To overcome antiviral RNA silencing, viruses express silencing-suppressor proteins. These viral proteins can target one or more key points in the silencing machinery. Here we show that in Sweet potato mild mottle virus (SPMMV, type member of the...