Article
Mutation of a Short Variable Region in HCpro Protein of Potato virus A Affects Interactions with a Microtubule-Associated Protein and Induces Necrotic Responses in Tobacco.
Molecular plant-microbe interactions : MPMI - 1 Jul 2013
Haikonen Tuuli, Rajamäki Minna-Liisa, Tian Yan-Ping, Valkonen Jari P T
Abstract excerpt
Helper component proteinase (HCpro) is a multifunctional protein of potyviruses (genus Potyvirus). HCpro of Potato virus A (PVA) interacts with the microtubule-associated protein HIP2 in host cells, and depletion of HIP2 reduces virus accumulation. This study shows that HCpro of Potato virus Y and Tobacco etch virus also interact with HIP2. The C-proximal portion of PVA HCpro determines the interaction with HIP2...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.