Article
Discriminating mutations of HC-Pro of zucchini yellow mosaic virus with differential effects on small RNA pathways involved in viral pathogenicity and symptom development.
Molecular plant-microbe interactions : MPMI - 1 Jan 2010
Wu Hui-Wen, Lin Shih-Shun, Chen Kuan-Chun, Yeh Shyi-Dong, Chua Nam-Hai
Abstract excerpt
Helper component-proteinase (HC-Pro), the gene-silencing suppressor of Potyvirus spp., interferes with microRNA (miRNA) and short-interfering RNA (siRNA) pathways. Our previous studies showed that three mutations of highly conserved amino acids of HC-Pro, R(180)I (mutation A), F(205)L (B), and E(396)N (C), of Zucchini yellow mosaic virus (ZYMV) affect symptom severity and viral pathogenicity. The mutant ZYMV GAC...
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