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Role of a Synonymous Mutation at Codon 178 in P1 That Attenuates Potato Virus Y-Induced Tobacco Vein Necrosis and Its Application for Expressing Human Interferon.

Molecular plant pathology - 1 Jun 2026

Liu De-Guo, Wang Yue-Yue, Zhu Qing, Huang Xin-Wei, Yan Xi-Ying, Jia Meng-Ao, Guo Yu-Shuang, Cao Ling-Gai, Jiang Jun, Li Xiang-Dong, Zhang Xiao-Lian, Tian Yan-Ping

Abstract excerpt

Plant virus-based vectors are gaining significant attention as bioreactors for recombinant protein production due to their broad host range, robust expression levels and cost-effectiveness; however, their practical utility is frequently constrained by severe viral pathogenicity. Notably, the utility of potato virus Y (PVY), the type member of the genus Potyvirus, is severely hampered by its elicitation of tobacco...

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PMID: 42348179
DOI: 10.1111/mpp.70304
PMCID: PMC13296828

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Role of a Synonymous Mutation at Codon 178 in P1 That Attenuates Potato Virus Y-Induced Tobacco Vein Necrosis and Its Application for Expressing Human Interferon.PMID 42348179Read ↗

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