Recent advances in the delivery and applications of nonviral CRISPR/Cas9 gene editing

Abstract excerpt

<title>Abstract</title> <p>The CRISPR (clustered regularly interspaced short palindromic repeats)/Cas9 genome editing system has been a major technological breakthrough that has brought revolutionary changes to genome editing for therapeutic and diagnostic purposes and precision medicine. With the advent of the CRISPR/Cas9 system, one of the critical limiting factors has been the safe and efficient delivery of th...

Topics

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• CRISPR and Genetic Engineering
• CRISPR-Cas Systems
• Disease Management
• Gene Editing
• Gene Targeting
• Genetic Therapy
• Models, Animal
• Organ Specificity

Identifiers and source

Literature Corpus work

1404a035-ee29-507c-bfeb-4a28119586d8

DOI

10.21203/rs.3.rs-2212281/v1