Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Trojan Horse-Like Vehicles for CRISPR-Cas Delivery: Engineering Extracellular Vesicles and Virus-Like Particles for Precision Gene Editing in Cystic Fibrosis

28 Apr 2025

Abstract excerpt

The advent of genome editing has kindled the hope to cure previously uncurable, life-threatening genetic diseases. However, whether this promise can be ultimately fulfilled depends on how efficiently gene editing agents can be delivered to therapeutically relevant cells. Over time, viruses have evolved into sophisticated, versatile, and biocompatible nanomachines that can be engineered to shuttle payloads to...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Extracellular vesicles in disease
Share to Parvovirus B19 Infection Studies
Share to RNA Interference and Gene Delivery

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 40295092
DOI: 10.1089/hum.2024.258

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Trojan Horse-Like Vehicles for CRISPR-Cas Delivery: Engineering Extracellular Vesicles and Virus-Like Particles for Precision Gene Editing in Cystic FibrosisPMID 40295092Read ↗

Gene Editing by Extracellular Vesicles.Semantic proximity Read ↗

CRISPR delivery with extracellular vesicles: Promises and challengesSemantic proximity Read ↗

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome EditingSemantic proximity Read ↗

Packaging and Uncoating of CRISPR/Cas Ribonucleoproteins for Efficient Gene Editing with Viral and Non-viral Extracellular NanoparticlesSemantic proximity Read ↗

VSV-G-Enveloped Vesicles for Traceless Delivery of CRISPR-Cas9Semantic proximity Read ↗

Efficient genome editing in the non-human primate brain using programmable extracellular vesiclesSemantic proximity Read ↗

A vesicle-based platform for high-efficiency, high-viability CRISPR/Cas9 knockout in primary human myeloid cellsSemantic proximity Read ↗

New Advances in Using Virus-like Particles and Related Technologies for Eukaryotic Genome Editing DeliverySemantic proximity Read ↗

An exosome-based gene delivery platform for cell-specific CRISPR/Cas9 genome editingSemantic proximity Read ↗

Advances in Nanoparticles as Non-Viral Vectors for Efficient Delivery of CRISPR/Cas9Semantic proximity Read ↗

A modular strategy for extracellular vesicle-mediated CRISPR-Cas9 delivery through aptamer-based loading and UV-activated cargo releaseSemantic proximity Read ↗

Generation of Cellular Biofactories for Scalable Production of Surface-Engineered Extracellular Vesicles via CRISPR Genome EditingSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.