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A novel tumor purity and immune infiltration-related model for predicting distant metastasis-free survival in prostate cancer

28 Nov 2023

Abstract excerpt

BACKGROUND: umor cells, immune cells and stromal cells jointly modify tumor development and progression. We aim to explore the potential effects of tumor purity on the immune microenvironment, genetic landscape and prognosis in prostate cancer (PCa). METHODS: Tumor purity of prostate cancer patients was extracted from The cancer genome atlas (TCGA). Immune cellular proportions were calculated by the CIBERSORT. To...

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PMID: 38017548
DOI: 10.1186/s40001-023-01522-8

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