Article
Genetic risk, incident gastric cancer, and healthy lifestyle: a meta-analysis of genome-wide association studies and prospective cohort study.
The Lancet. Oncology - 1 Oct 2020
Jin Guangfu, Lv Jun, Yang Ming, Wang Mengyun, Zhu Meng, Wang Tianpei, Yan Caiwang, Yu Canqing, Ding Yanbing, Li Gang, Ren Chuanli, Ni Jing, Zhang Ruoxin, Guo Yu, Bian Zheng, Zheng Yan, Zhang Nasha, Jiang Yue, Chen Jiaping, Wang Yanong, Xu Dazhi, Zheng Hong, Yang Ling, Chen Yiping, Walters Robin, Millwood Iona Y, Dai Juncheng, Ma Hongxia, Chen Kexin, Chen Zhengming, Hu Zhibin, Wei Qingyi, Shen Hongbing, Li Liming
Abstract excerpt
BACKGROUND: Genetic variants and lifestyle factors have been associated with gastric cancer risk, but the extent to which an increased genetic risk can be offset by a healthy lifestyle remains unknown. We aimed to establish a genetic risk model for gastric cancer and assess the benefits of adhering to a healthy lifestyle in individuals with a high genetic risk. METHODS: In this meta-analysis and prospective...
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