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Article

Polygenic Risk Scores for Prediction of Gastric Cancer Based on Bioinformatics Screening and Validation of Functional lncRNA SNPs.

Clinical and translational gastroenterology - 18 Nov 2021

Duan Fujiao, Song Chunhua, Wang Peng, Ye Hua, Dai Liping, Zhang Jianying, Wang Kaijuan

Abstract excerpt

INTRODUCTION: Single-nucleotide polymorphisms (SNPs) are used to stratify the risk of gastric cancer. However, no study included gastric cancer-related long noncoding RNA (lncRNA) SNPs into the risk model for evaluation. This study aimed to replicate the associations of 21 lncRNA SNPs and to construct an individual risk prediction model for gastric cancer. METHODS: The bioinformatics method was used to screen...

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Computational Biology
Genetic Predisposition to Disease
Logistic Models
Polymorphism, Single Nucleotide

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk Assessment

RNA, Long Noncoding

Stomach Neoplasms

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Identifiers

PMID: 34797779
DOI: 10.14309/ctg.0000000000000430
PMCID: PMC8604006

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