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Article

NT5C2 methylation regulatory interplay between DNMT1 and insulin receptor in type 2 diabetes.

Scientific reports - 30 Sept 2020

Chen Yng-Tay, Lin Wei-De, Liao Wen-Ling, Tsai Ya-Ching, Liao Jiunn-Wang, Tsai Fuu-Jen

Abstract excerpt

Epigenetics alternation of non-genetic variation and genome-wide association study proven allelic variants may associate with insulin secretion in type 2 diabetes (T2D) development. We analyzed promoter DNA methylation array to evaluate the associated with increased susceptibility to T2D (30 cases, 10 controls) and found 1,091 gene hypermethylated in promoter regions. We performed the association study of T2D and...

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Share to 5'-Nucleotidase
Share to Antigens, CD
Share to DNA (Cytosine-5-)-Methyltransferase 1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Fucosyltransferases

Share to Insulin

Share to Insulin-Secreting Cells

Share to Receptor, Insulin

Source

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Identifiers

PMID: 32999320
DOI: 10.1038/s41598-020-71336-9
PMCID: PMC7527562

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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