Article
DNA Methylation Changes Associated With Type 2 Diabetes and Diabetic Kidney Disease in an East Asian Population.
The Journal of clinical endocrinology and metabolism - 27 Sept 2021
Kim Hakyung, Bae Jae Hyun, Park Kyong Soo, Sung Joohon, Kwak Soo Heon
Abstract excerpt
CONTEXT: There is a growing body of evidence that epigenetic changes including DNA methylation influence the risk of type 2 diabetes (T2D) and its microvascular complications. OBJECTIVE: We conducted a methylome-wide association study (MWAS) to identify differentially methylated sites (DMSs) of T2D and diabetic kidney disease (DKD) in a Korean population. METHODS: We performed an MWAS in 232 participants with T2D...
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