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DNA methylation landscapes in the pathogenesis of type 2 diabetes mellitus

28 Jun 2018

Abstract excerpt

Although genetic variations and environmental factors are vital to the development and progression of type 2 diabetes mellitus (T2DM), emerging literature suggest that epigenetics, especially DNA methylation, play a key role in the pathogenesis of T2DM by affecting insulin secretion of pancreatic β cells and the body's resistance to insulin. Previous studies have elucidated how DNA methylation interacted with...

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PMID: 29988495
DOI: 10.1186/s12986-018-0283-x

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