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DNA methylation: a cause and consequence of type 2 diabetes

16 Dec 2019

Abstract excerpt

DNA methylation is a relatively stable epigenetic modification that can regulate and stabilize gene expression patterns and hence establish cell identity. Because metabolic intermediates are key factors of DNA methylation and demethylation, perturbations in metabolic homeostasis can trigger alterations in cell-specific patterns of DNA methylation and contribute to disease development, including type 2 diabetes...

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Identifiers

PMID: 31896238
DOI: 10.5808/gi.2019.17.4.e38

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