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Epigenetics and Beyond: Targeting Histone Methylation to Treat Type 2 Diabetes Mellitus

11 Jan 2022

Abstract excerpt

Diabetes mellitus is a global public health challenge with high morbidity. Type 2 diabetes mellitus (T2DM) accounts for 90% of the global prevalence of diabetes. T2DM is featured by a combination of defective insulin secretion by pancreatic β-cells and the inability of insulin-sensitive tissues to respond appropriately to insulin. However, the pathogenesis of this disease is complicated by genetic and...

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PMID: 35087408
DOI: 10.3389/fphar.2021.807413

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