Article
Cooperativity of membrane-protein and protein-protein interactions control membrane remodeling by epsin 1 and affects clathrin-mediated endocytosis.
Cellular and molecular life sciences : CMLS - 1 Mar 2021
Kroppen Benjamin, Teske Nelli, Yambire King F, Denkert Niels, Mukherjee Indrani, Tarasenko Daryna, Jaipuria Garima, Zweckstetter Markus, Milosevic Ira, Steinem Claudia, Meinecke Michael
Abstract excerpt
Membrane remodeling is a critical process for many membrane trafficking events, including clathrin-mediated endocytosis. Several molecular mechanisms for protein-induced membrane curvature have been described in some detail. Contrary, the effect that the physico-chemical properties of the membrane have on these processes is far less well understood. Here, we show that the membrane binding and curvature-inducing...
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