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Article

Cells Control BIN1-Mediated Membrane Tubulation by Altering the Membrane Charge.

Journal of molecular biology - 14 Feb 2020

Gowrisankaran Sindhuja, Wang Zuoneng, Morgan David G, Milosevic Ira, Mim Carsten

Abstract excerpt

The Bridging integrator 1 (BIN1)/Amphiphysin/Rvs (BAR) protein family is an essential part of the cell's machinery to bend membranes. BIN1 is a muscle-enriched BAR protein with an established role in muscle development and skeletal myopathies. Here, we demonstrate that BIN1, on its own, is able to form complex interconnected tubular systems in vitro, reminiscent of t-tubule system in muscle cells. We further...

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Identifiers

PMID: 31857086
DOI: 10.1016/j.jmb.2019.12.001

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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