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Article

A Signature-Tagged Mutagenesis (STM)-based murine-infectivity assay for Cryptococcus neoformans.

Journal of microbiology (Seoul, Korea) - 1 Oct 2020

Jung Kwang-Woo, Lee Kyung-Tae, Bahn Yong-Sun

Abstract excerpt

Signature-tagged mutagenesis (STM) is a high-throughput genetic technique that can be used to investigate the function of genes by constructing a large number of mutant strains with unique DNA identification tags, pooling them, and screening them for a particular phenotypic trait. STM was first designed for the identification of genes that contribute to the virulence or infectivity of a pathogen in its host....

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PMID: 32989639
DOI: 10.1007/s12275-020-0341-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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