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Article

Signature-tagged mutagenesis.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2014

Kukavica-Ibrulj Irena, Levesque Roger C

Abstract excerpt

Signature-tagged mutagenesis (STM) is a genome-wide functional screening assay based upon an insertional mutation technique to identify mutants having a particular phenotype from a mixed population. The selection phenotype is either negative or positive for identification of mutations in genes which will impact the host as having a diminished or enhanced adaptation to a defined environment. STM has subsequently...

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PMID: 24818931
DOI: 10.1007/978-1-4939-0473-0_41

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Source receipt: pubmed, retrieved 7 Sept 2026.

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