Article
Genetic variability of molecules involved in the disease pathogenesis in Leishmania infection.
Experimental parasitology - 1 Nov 2020
Sánchez Luquez Karen Y, Zerpa Olga, Paz-Villarraga César A, Fernández-Mestre Mercedes
Abstract excerpt
Macrophages are the primary host cell for Leishmania parasites, by Toll like receptors (TLR-MyD88) that are central components of the innate and adaptive immunity against leishmania infection. The CD40/CD40L interaction has also been shown to be important in resistance to various protozoa. In this context, one of the most important properties of suppressors of cytokine signalling (SOCS) proteins, especially SOCS1...
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