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Article

Toll-like receptor 4 polymorphisms predispose to cutaneous leishmaniasis.

Microbes and infection - 1 Mar 2011

Ajdary Soheila, Ghamilouie Mir-Mostafa, Alimohammadian Mohammad-Hossein, Riazi-Rad Farhad, Pakzad Saeed-Reza

Abstract excerpt

The clinical spectrum of cutaneous leishmaniasis (CL) is extremely variable. Studies in experimental leishmaniasis have revealed a role for TLR4 in control of infection. In the present study the associations between TLR4 mutations (Asp299Gly and Thr399Ile) with outcome of CL have been investigated. Genotyping for Asp299Gly and Thr399Ile was performed in patients with chronic (N = 22) and acute (N = 61) CL,...

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Source

Identifiers

PMID: 21056683
DOI: 10.1016/j.micinf.2010.10.018

Genes

TLR4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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