Article
Polymorphisms in androgen signaling pathway predisposing to prostate cancer.
Molecular and cellular endocrinology - 5 Sept 2012
Schleutker Johanna
Abstract excerpt
Prostate cancer is the most frequent male malignancy diagnosed in western countries and androgens are known to mediate key physiological processes in prostate tissue. Since endogenous androgens have long been considered to be risk factors for prostate cancer, genes involved in androgen biosynthesis and metabolism have been extensively studied. In this review, association of androgen pathway genes, their...
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