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DNA Methylation Events in Transcription Factors and Gene Expression Changes in Colon Cancer

1 Sept 2020

Abstract excerpt

Aim: Gain insight about the role of DNA methylation in the malignant growth of colon cancer. Patients & methods: Methylation and gene expression from 90 adjacent-tumor paired tissues and 48 healthy tissues were analyzed. Tumor genes whose change in expression was explained by changes in methylation were identified using linear models adjusted for tumor stromal content. Results: No differences in methylation were...

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PMID: 32957849
DOI: 10.2217/epi-2020-0029

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