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A genome-wide DNA methylation study in colorectal carcinoma

23 Jun 2011

Abstract excerpt

BACKGROUND: We performed a genome-wide scan of 27,578 CpG loci covering 14,475 genes to identify differentially methylated loci (DML) in colorectal carcinoma (CRC). METHODS: We used Illumina's Infinium methylation assay in paired DNA samples extracted from 24 fresh frozen CRC tissues and their corresponding normal colon tissues from 24 consecutive diagnosed patients at a tertiary medical center. RESULTS: We found...

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PMID: 21699707
DOI: 10.1186/1755-8794-4-50

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