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Identification of differentially expressed genes regulated by methylation in colon cancer based on bioinformatics analysis

14 Jul 2019

Abstract excerpt

BACKGROUND: DNA methylation, acknowledged as a key modification in the field of epigenetics, regulates gene expression at the transcriptional level. Aberrant methylation in DNA regulatory regions could upregulate oncogenes and downregulate tumor suppressor genes without changing the sequences. However, studies of methylation in the control of gene expression are still inadequate. In the present research, we...

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PMID: 31341364
DOI: 10.3748/wjg.v25.i26.3392

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