Article
Personalized drug testing in a patient with non-small-cell lung cancer using cultured cancer cells from pleural effusion.
The Journal of international medical research - 1 Sept 2020
Wu Ming, Hong Guodai, Chen Yu, Ye Lina, Zhang Kang, Cai Kaihong, Yang Huadong, Long Xiang, Gao Wenbin, Li Hui
Abstract excerpt
OBJECTIVE: Patients with non-small-cell lung cancer (NSCLC) and primary or acquired resistance do not respond to targeted drugs. We explored whether cancer cells can be cultured from liquid biopsies from patients with primary resistance to tyrosine kinase inhibitors (TKIs). We aimed to predict patients' responses to drugs according to in vitro drug testing results. METHODS: Cancer cell cultures were established...
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