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Article

Pioneer of prostate cancer: past, present and the future of FOXA1.

Protein & cell - 1 Jan 2021

Teng Mona, Zhou Stanley, Cai Changmeng, Lupien Mathieu, He Housheng Hansen

Abstract excerpt

Prostate cancer is the most commonly diagnosed non-cutaneous cancers in North American men. While androgen deprivation has remained as the cornerstone of prostate cancer treatment, resistance ensues leading to lethal disease. Forkhead box A1 (FOXA1) encodes a pioneer factor that induces open chromatin conformation to allow the binding of other transcription factors. Through direct interactions with the Androgen...

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Share to Epithelial-Mesenchymal Transition
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32946061
DOI: 10.1007/s13238-020-00786-8
PMCID: PMC7815845

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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