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Post-mortem ventricular cerebrospinal fluid cell-free-mtDNA in neurodegenerative disease

17 Sept 2020

Abstract excerpt

Cell-free mitochondrial DNA (cfmtDNA) is detectable in almost all human body fluids and has been associated with the onset and progression of several complex traits. In-life assessments indicate that reduced cfmtDNA is a feature of neurodegenerative diseases such as Parkinson's disease, Alzheimer's disease and multiple sclerosis. However, whether this feature is conserved across all neurodegenerative diseases and...

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PMID: 32943697
DOI: 10.1038/s41598-020-72190-5

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