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Small RNAs in plasma extracellular vesicles define biomarkers of premanifest changes in Huntington’s disease

2023-12-04

Abstract excerpt

Despite the advances in the understanding of Huntington’s disease (HD), there is the need for molecular biomarkers to categorize mutation-carriers during the preclinical stage of the disease preceding the functional decline. Small RNAs (sRNAs) are a promising source of biomarkers since their expression levels are highly sensitive to pathobiological processes. Here, using an optimized method for plasma extracellula...

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Literature Corpus work
60cc9f69-2379-5548-99e0-bfb9e88ba3e7
DOI
10.1101/2023.12.01.568823
Open publication

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Small RNAs in plasma extracellular vesicles define biomarkers of premanifest changes in Huntington’s diseaseDOI 10.1101/2023.12.01.568823
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