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Cell-free mitochondrial DNA in progressive multiple sclerosis

8 Aug 2018

Abstract excerpt

Recent studies have linked cell-free mitochondrial DNA (ccf-mtDNA) to neurodegeneration in both Alzheimer's and Parkinson's disease, raising the possibility that the same phenomenon could be seen in other diseases which manifest a neurodegenerative component. Here, we assessed the role of circulating cell-free mitochondrial DNA (ccf-mtDNA) in end-stage progressive multiple sclerosis (PMS), where neurodegeneration...

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PMID: 30098422
DOI: 10.1016/j.mito.2018.07.008

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