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Article

Mitochondrial DNA in CSF distinguishes LRRK2 from idiopathic Parkinson's disease.

Neurobiology of disease - 1 Oct 2016

Podlesniy Petar, Vilas Dolores, Taylor Peggy, Shaw Leslie M, Tolosa Eduard, Trullas Ramon

Abstract excerpt

Mitochondrial DNA regulates mitochondrial function which is altered in both idiopathic and familial forms of Parkinson's disease. To investigate whether these two disease forms exhibit an altered regulation of mitochondrial DNA we measured cell free mitochondrial DNA content in cerebrospinal fluid (CSF) from idiopathic and LRRK2-related Parkinson's disease patients. The concentration of mitochondrial DNA was...

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Identifiers

PMID: 27260835
DOI: 10.1016/j.nbd.2016.05.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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