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Article

Genetic profiling of primary and secondary tumors from patients with lung adenocarcinoma and bone metastases reveals targeted therapy options.

Molecular medicine (Cambridge, Mass.) - 17 Sept 2020

Huang Long, Jiang Xiao-Liu, Liang Hong-Bin, Li Jian-Cheng, Chin Li-Han, Wei Jian-Ping, Wang Rui-Ru, Cai Jing, Xiong Qiang, Wang Lien-Tu, Cram David S, Liu An-Wen

Abstract excerpt

BACKGROUND: Patients newly diagnosed with lung adenocarcinoma with bone metastases (LABM) have poor survival rates after treatment with conventional therapies. To improve outcomes, we retrospectively investigated whether the application of a more comprehensive genetic test of tumor biopsies samples from LABM patients could provide the basis for treatment with more effective tyrosine kinase inhibitors (TKIs)...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 32942985
DOI: 10.1186/s10020-020-00197-9
PMCID: PMC7499871

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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