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Article

Pharmacogenetic determinants of thiopurines in an Indian cohort.

Pharmacological reports : PR - 1 Feb 2021

Naushad Shaik Mohammad, Janaki Ramaiah Mekala, Kutala Vijay Kumar, Hussain Tajamul, Alrokayan Salman A

Abstract excerpt

BACKGROUND: Several genetic variants of thiopurine metabolic pathway are associated with 6-thiopurine-mediated leucopenia. A population-based evaluation of these variants lays the foundation for Pharmacogenetic-guided thiopurine therapy. METHODS: A total of 2000 subjects were screened for the pharmacogenetic determinants using the infinium global screening array (GSA). The functional relevance of these variants...

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PMID: 32935219
DOI: 10.1007/s43440-020-00158-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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