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Article

Association of sex and APOE ε4 with brain tau deposition and atrophy in older adults with Alzheimer's disease.

Theranostics - 1 Jan 2020

Yan Shaozhen, Zheng Chaojie, Paranjpe Manish D, Li Jian, Benzinger Tammie L S, Lu Jie, Zhou Yun

Abstract excerpt

The objective of this study was to assess the association of sex and the apolipoprotein E (APOE) ε4 allele with brain tau deposition and atrophy in older adults with Alzheimer's disease (AD) using quantitative 18F-AV-1451 positron emission tomography (PET) and magnetic resonance imaging (MRI). Methods: Preprocessed 18F-AV-1451 tau PET, raw T1-weighted structural MR images, demographic information, cerebrospinal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 32929366
DOI: 10.7150/thno.48522
PMCID: PMC7482805

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