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Article

Aberration of Serum and Tissue N-Glycans in Mouse β1,4-GalT1 Y286L Mutant Variants.

Glycoconjugate journal - 1 Dec 2020

Cao Ran, Zhang Tian-Chan, Chen Ya-Ran, Cao Cui, Chen Huan, Huang Yi-Fan, Fujita Morihisa, Liu Li, Voglmeir Josef

Abstract excerpt

β1,4-GalT1 is a type II membrane glycosyltransferase. It catalyzes the production of lactose in the lactating mammary gland and is supposedly also involved in the galactosylation of terminal GlcNAc of complex-type N-glycans. In-vitro studies of the bovine β4Gal-T1 homolog showed that replacing a single residue of tyrosine with leucine at position 289 alters the donor substrate specificity from UDP-Gal to...

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Identifiers

PMID: 32926333
DOI: 10.1007/s10719-020-09946-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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