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Article

Polypeptide N-acetylgalactosaminyltransferase-Associated Phenotypes in Mammals.

Molecules (Basel, Switzerland) - 10 Sept 2021

Kato Kentaro, Hansen Lars, Clausen Henrik

Abstract excerpt

Mucin-type O-glycosylation involves the attachment of glycans to an initial O-linked N-acetylgalactosamine (GalNAc) on serine and threonine residues on proteins. This process in mammals is initiated and regulated by a large family of 20 UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferases (GalNAc-Ts) (EC 2.4.1.41). The enzymes are encoded by a large gene family (GALNTs). Two of these genes, GALNT2 and...

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Identifiers

PMID: 34576978
DOI: 10.3390/molecules26185504
PMCID: PMC8472655

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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