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Article

Genome-wide association study of peripheral neuropathy with D-drug-containing regimens in AIDS Clinical Trials Group protocol 384.

Journal of neurovirology - 1 Jun 2014

Leger Paul D, Johnson Daniel H, Robbins Gregory K, Shafer Robert W, Clifford David B, Li Jun, McLaren Paul J, Haas David W

Abstract excerpt

Stavudine (d4T) was, until recently, one of the most widely prescribed antiretroviral drugs worldwide. While there has been a major shift away from d4T use in resource-limited countries, a large number of patients have previously received (or continue to receive) d4T, and many have developed peripheral neuropathy. The identification of genetic predictors of increased risk might suggest novel therapeutic targets...

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Source

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Identifiers

PMID: 24554482
DOI: 10.1007/s13365-014-0235-9
PMCID: PMC4114519

Genes

LITAF
NEFL

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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