Article
Association of ERAP2 polymorphisms in Colombian HLA-B27+ or HLA-B15+ patients with SpA and its relationship with clinical presentation: axial or peripheral predominance.
RMD open - 1 Sept 2020
Londono John, Santos Ana M, Rueda Juan C, Calvo-Paramo Enrique, Burgos-Vargas Ruben, Vargas-Alarcon Gilberto, Martinez-Rodriguez Nancy, Arias-Correal Sofia, Muñoz Guisselle-Nathalia, Padilla Diana, Cuervo Francy, Reyes-Martinez Viviana, Bernal-Macías Santiago, Villota-Eraso Catalina, Avila-Portillo Luz M, Romero Consuelo, Medina Juan F
Abstract excerpt
OBJECTIVE: To determine the association between endoplasmic reticulum aminopeptidase (ERAP)1 and ERAP2 single-nucleotide polymorphisms (SNPs) and human leukocyte antigens (HLA)-B27+ or HLA-B15+ patients with spondyloarthritis (SpA). METHODS: 104 patients with SpA according to Assessment of Spondyloarthritis International Society criteria were included in the study. HLA typing was performed by PCR. The...
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