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Article

Protective effect of an ERAP1 haplotype in ankylosing spondylitis: investigating non-MHC genes in HLA-B27-positive individuals.

Rheumatology (Oxford, England) - 1 Dec 2013

Bettencourt Bruno Filipe, Rocha Fabiana Leal, Alves Helena, Amorim Rosa, Caetano-Lopes Joana, Vieira-Sousa Elsa, Pimentel-Santos Fernando, Lima Manuela, Porto Graça, Branco Jaime C, Fonseca João Eurico, Bruges-Armas Jácome

Abstract excerpt

OBJECTIVE: The association of non-MHC genes with AS has been recently suggested. We aimed to investigate the association of the ERAP1, IL23R and TNFSF15 regions and the susceptibility to and protection from AS in HLA-B27-positive individuals. METHODS: A total of 200 unrelated AS patients and 559 healthy unrelated subjects, all HLA-B27 positive, were tested. Twenty single nucleotide polymorphisms (SNPs) were...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24046467
DOI: 10.1093/rheumatology/ket269

Genes

ERAP1
TNFSF15

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Protective effect of an ERAP1 haplotype in ankylosing spondylitis: investigating non-MHC genes in HLA-B27-positive individuals.PMID 24046467Read ↗

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Associations between ERAP1 polymorphisms and ankylosing spondylitis susceptibility in HLA-B27 positive population: a Meta-analysis and bioinformatics analysis.Semantic proximity Read ↗

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Genome-wide association study of ankylosing spondylitis identifies non-MHC susceptibility loci.Semantic proximity Read ↗

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