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Article

Association of the genetic variants in the endoplasmic reticulum aminopeptidase 2 gene with ankylosing spondylitis susceptibility.

International journal of rheumatic diseases - 1 Apr 2021

Ebrazeh Mehrdad, Ezzatifar Fatemeh, Torkamandi Shahram, Mohammadi Fatemeh Sadat, Salimifard Sevda, Gowhari Shabgah Arezoo, Hemmatzadeh Maryam, Aslani Saeed, Babaie Farhad, Jadidi-Niaragh Farhad, Gholizadeh Navashenaq Jamshid, Mohammadi Hamed

Abstract excerpt

BACKGROUND: Genetic polymorphisms in the endoplasmic reticulum aminopeptidase gene ERAP2 has been attributed with the etiopathogenesis of ankylosing spondylitis (AS). Here we assessed the association of ERAP2 gene single nucleotide polymorphisms (SNPs) with AS predisposition in Iranian patients and determined their effect on the inflammatory state of the patients. METHODS: For genotyping of rs2548538, rs2287988,...

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Identifiers

PMID: 33550689
DOI: 10.1111/1756-185X.14079

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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