Article
Association between endoplasmic reticulum aminopeptidase-1 (ERAP-1) and susceptibility to ankylosing spondylitis in Iran.
Iranian journal of allergy, asthma, and immunology - 1 Dec 2012
Mahmoudi Mahdi, Jamshidi Ahmad Reza, Amirzargar Ali Akbar, Farhadi Elham, Nourijelyani Keramat, Fallahi Sasan, Oraei Mona, Noori Sahar, Nicknam Mohammad Hossein
Abstract excerpt
Ankylosing spondylitis (AS) is an inflammatory arthritis, which affects mainly spine and sacroiliac joints. According to recent studies, ERAP1 is the second most common candidate gene for AS susceptibility after HLA-B27. The aim of this study was to determine the association of ERAP1 gene polymorphisms with AS in Iranian population.The study group comprised 387 Iranian AS patients and 316 healthy controls from...
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