Association of Endoplasmic Reticulum Aminopeptidase 1 Gene Polymorphism with Susceptibility and Severity of Axial Spondyloarthritis in Egyptian Population: A Single-center Case-Control Study.

doi:10.4103/aam.aam_180_23

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Article

Association of Endoplasmic Reticulum Aminopeptidase 1 Gene Polymorphism with Susceptibility and Severity of Axial Spondyloarthritis in Egyptian Population: A Single-center Case-Control Study.

Annals of African medicine - 1 Jul 2024

Saad Mohamed Ahmed, Abdul-Sattar Amal Bakry, Abdelal Ibrahim Tharwat, Barak Ahmed

Abstract excerpt

BACKGROUND: Axial spondyloarthritis (axSpA) is a systemic, progressive, autoimmune disease. Complex interactions between environmental factors and host immune responses are the origin of axSpA. Together with human leukocyte antigen (HLA-B27), endoplasmic reticulum aminopeptidase 1 (ERAP1) gene is a potential non-HLA contributor to axSpA susceptibility. AIM: This study aimed to identify the role of ERAP1...

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PMID: 39034571
DOI: 10.4103/aam.aam_180_23
PMCID: PMC11364326

Genes

ERAP1

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