Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Therapeutic Fc‐fusion proteins: Current analytical strategies

22 Sept 2020

Abstract excerpt

Fc-Fusion proteins represent a successful class of biopharmaceutical products, with already 13 drugs approved in the European Union and United States as well as three biosimilar versions of etanercept. Fc-Fusion products combine tailored pharmacological properties of biological ligands, together with multiple functions of the fragment crystallizable domain of immunoglobulins. There is a great diversity in terms...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Monoclonal and Polyclonal Antibodies Research
Share to Protein purification and stability
Share to Viral Infectious Diseases and Gene Expression in Insects

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 32914936
DOI: 10.1002/jssc.202000765

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Therapeutic Fc‐fusion proteins: Current analytical strategiesPMID 32914936Read ↗

Fc γ receptor compositional heterogeneity: Considerations for immunotherapy development.Semantic proximity Read ↗

Identification of Engineered IMGT Fc Variants in IMGT/mAb-DB Therapeutic Antibodies and Fusion proteinsSemantic proximity Read ↗

Update on Fc receptor-like (FCRL) family: new immunoregulatory players in health and diseasesSemantic proximity Read ↗

A robust nanoscale RP HPLC-MS approach for sensitive Fc proteoform profiling of IgG allotypesSemantic proximity Read ↗

Engineering the fragment crystallizable (Fc) region of human IgG1 multimers and monomers to fine-tune interactions with sialic acid-dependent receptors.Semantic proximity Read ↗

Monoclonal Antibody Engineering and Design to Modulate FcRn Activities: A Comprehensive ReviewSemantic proximity Read ↗

Evaluation of an FcRn affinity chromatographic method for IgG1-type antibodies and evaluation of IgG variants.Semantic proximity Read ↗

Translational Proteomics for Transfusion Medicine: Resolution of the IVIG Proteomes of Different Geographically Sourced and Prepared IVIG ImmunotherapiesSemantic proximity Read ↗

Protein engineering of antibody fragments for pharmaceutical productionSemantic proximity Read ↗

Profiling the Biophysical Developability Properties of Common IgG1 Fc Effector Silencing VariantsSemantic proximity Read ↗

Current development of Fc gamma receptors (FcγRs) in diagnostics: a reviewSemantic proximity Read ↗

Afucosylated immunoglobulin G responses are a hallmark of enveloped virus infections and show an exacerbated phenotype in COVID-19Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.